Survival data were generated as Kaplan–Meier curves and were compared by log‐rank tests. A multivariate Cox proportional hazards model was used to analyze the risk factors.
eBook Title: Heterogeneous Survival Between Stage IIA and Stage IIIA Colon Cancer when Different Numbers of Lymph Nodes are Harvested
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Abstract : Background: We aim to compare the prognosis between patients with stage IIA and stage IIIA colon cancer. Methods: We analysed patients with stage IIA or stage IIIA colon cancer based on data from the US Surveillance, Epidemiology, and End Results (SEER) database. Survival data were generated as Kaplan–Meier curves and were compared by log‐rank tests. A multivariate Cox proportional hazards model was used to analyze the risk factors. Results: In total, 43 379 patients (38 784 stage IIA and 4595 stage IIIA) were included from the SEER database. A Kaplan–Meier analysis showed no significant difference between patients with stage IIA and IIIA colon cancer ( P = 0.547). In the subgroup of patients with number of lymph nodes harvested (LNH) ≥12, a multivariate analysis showed that compared with stage IIA patients, stage IIIA patients were more likely to have a poorer cancer‐specific survival (CSS) (hazard ratio (HR) 1.252, 95% confidence interval (CI) 1.095–1.431, P = 0.001). In the subgroup of patients with LNH
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